bankrupt
blasted
blighted
broken
burned-out
desolated
destroyed
devastated
devitalized
disabled
done
done for
done in
done up
down-and-out
drained
effete
emptied
enervated
enfeebled
eviscerated
exhausted
fallen
far-gone
fatigued
finished
frazzled
gone to pot
in ruins
incapacitated
irremediable
jaded
kaput
laid low
overthrown
played out
pooped
ravaged
ruined
ruinous
run-down
sapped
shotten
spent
spoiled
tired
undone
used up
wasted
weakened