Gordian knot
abstruseness
adverse circumstances
adversity
affliction
aggravation
agreement to disagree
altercation
annoyance
arduousness
asperity
bad news
bedevilment
beef
bickering
blight
block
blockade
bore
bother
botheration
bothersomeness
bottleneck
bummer
burden
burthen
care
cargo
catch
cavil
challenge
charge
complexity
complication
controversy
cordon
crabbedness
crampedness
crashing bore
cross
cross-purposes
crux
cumbrance
curse
curtain
deadweight
deepness
demurral
difficile
difficult
God
account
bay
cause
change
children
circumstance
conflict
danger
deal
disaster
dissuasion
distinction
distress
end
error
failure
hat
importance
knowledge
measure
necessity
objective
peace
peril
poem
poet
problem
secret
towns
trouble
wave
weakness
within