aggravation
annoyance
ass
bad news
bedevilment
besetment
bore
bother
botheration
bothersomeness
burden
buttonholer
crashing bore
devilment
difficulty
dogging
downer
drag
drip
dryasdust
dusty
exasperation
flat tire
frightful bore
harassment
harrying
hassle
headache
hounding
humdrum
inconvenience
irritant
irritation
molestation
nag
obstacle
ordeal
persecution
pest
pester
pesterer
pill
plague
problem
proser
tease
tormenter
disagreeable person
unpleasant person
blunder
complication
distraction
fuss
hardship
hindrance
humiliation
misunderstanding
outrage
scandal
torment
uproar