disagreeable
adverse
antagonistic
conflicting
contrary
counter
counteractive
detrimental
difficult
draining
exhausting
fatiguesome
fatiguing
grueling
hard
harmful
hostile
in opposition
inimical
killing
miserable
not easy
opposed
opposing
opposite
punishing
rigorous
sinister
straining
tiresome
tiring
toilsome
troublesome
troublous
trying
unfavorable
untoward
weariful
wearing
wearisome
wearying
wretched
stress
Embarrass
arduous
daunt
debilitate
disruptive
frighten
frustrate
hectic
inconvenient
irksome
life-threatening
messy
onerous
risky
scary
time-consuming
traumatic
unsettle
successful
unsuccessful