unfortunate
adverse
afflictive
awful
baleful
baneful
black
cataclysmal
cataclysmic
catastrophic
consuming
consumptive
deadly
demolishing
demolitionary
deplorable
depredatory
desolating
destroying
destructive
devastating
dire
disastrous
distressful
distressing
doomful
dreadful
fatal
fateful
fratricidal
grievous
heartbreaking
internecine
lamentable
miserable
nihilist
nihilistic
pernicious
ravaging
regrettable
ruining
ruinous
sad
debilitate
direful
disgraceful
humiliate
ignominious
irreparable
momentous
pitiable
stressful
tragical
unavoidable
unforeseeable
unforeseen
untoward