affliction
albatross
bale
bitter cup
bitter draft
bitter draught
bitter pill
burden
burden of care
burdening
burthen
cankerworm of care
care
cargo
charge
charging
check
client
clog
cross
crown of thorns
cumber
cumbrance
curse
deadweight
dependent
difficulty
disadvantage
distress
drag
embarrassment
freight
gall
gall and wormwood
grievance
hamper
handicap
hardship
hindrance
impedance
impediment
impedimenta
imposition
inconvenience
incubus
incumbency
incumbrance
distraction
drawback
easements
interloper
liens
nuisance
stumbling-block
trespasser
verbiage